As such we can't tell if Mass Effect 5 is an Andromeda follow-up or another game taking place in the Milky Way.
On the other hand, it could just mean that this craft just belongs to a civilian organization, like the Andromeda initiative. This fits with an interesting observation from Rock Paper Shotgun's Imogen Beckhelling, who believes that one of the silhouetted figures in the background is an Angara, a race of aliens introduced in Andromeda. In Mass Effect: Andromeda, the game was centered around humans and other races from the Milky Way galaxy arriving in the Andromeda galaxy, after a 600-year journey.
As it uses two letters and one number like Mass Effect: Andromeda's ND1 Nomad, rather than the two-number designations of original trilogy craft like the M35 Mako, M44 Hammerhead and UT-47 Kodiak, we can infer that the new game will be a sequel to Andromeda.
